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Faculty Profile

Jay Whelan

Jay Whelan - click to enlarge

Education
Ph.D., Nutrition Science, Penn State University, 1988

M.P.H., Nutrition, University of North Carolina, 1982

B.A., Biochemistry, Southern Connecticut State University,1976

Professional Experience
2002-present Department Head, Department of Nutrition, University of Tennessee

2001-present Professor, Department of Nutrition, University of Tennessee

1996 - 2001 Associate Professor, Department of Nutrition, University of Tennessee

1991 - 1996 Assistant Professor, Department of Nutrition, University of Tennessee

1988 - 1991 Senior Research Associate (Supervisor of Research), Lipids Research Laboratory, Institute of Food Science, Cornell University

1988 Post-doctoral Fellow, Center for Air and Environmental Studies, Penn State University

1982 PH Block Field Experience, Palm Beach County Public Health, West Palm Beach, FL

1981 Clinical Dietetics Internship, Duke University Medical Center, Durham, NC

1976-1979 Instructor, United States Naval Academy, Annapolis, MD

Publications (since 2001) (out of 60 publications)
• Whelan, J. 2005. Innovative Dietary Sources of n-3 Fatty Acids. Annual Review of Nutrition, Vol 24, (projected publication date 2005)

• Whelan, J. and McEntee, M.F. 2004. Dietary N-6 Polyunsaturated Fatty Acids and Intestinal Tumorigenesis. J. Nutr. 134, 3421S-3426S.

• Whelan, J., McEntee, M.F. and Baek, S.J. 2004. Dietary Polyunsaturated Fatty Acids, Eicosanoids, and Intestinal Tumorigenesis. In: Bioactive Lipids in Cancer. Carcinogenic and Anticarcinogenic Food Components (Ed., Sikorski, Z. E.) CRC Press. Boca Raton, FL. (In press)

• Ziegler, C.C., McEntee, M.F., Rainwater, L. and Whelan, J. 2004. Dietary Resveratrol Does Not Affect Intestinal Tumorigenesis in the ApcMin/+ Mice. J. Nutr. 134, 5-10.

• Whelan, J. and McEntee, M.F. 2003. NSAIDs, Prostaglandins and APC-Driven Intestinal Tumorigenesis. In: Cyclooxygenase-2 Blockade in Cancer Prevention and Therapy (Ed., Harris, R.E.) Humana Press, Inc.. Totowa, NJ

• McEntee, M.F. and Whelan, J. 2002. Dietary Polyunsaturated Fatty Acids and Colorectal Neoplasia. Biomedicine and Pharmacotherapy 56, 380-387.

• Kim, S, Whelan, J. and Moustaid-Moussa, N. 2002. Angiotensin II Increases Leptin Secretion in Adipocytes via a Prostaglandin-Independent Mechanism. J. Nutr. 132, 1135-1140.

• Petrik, M.H., McEntee, M.F., Jull, B., Shi, H., Zemel, M.B. and Whelan, J. 2002. Prostaglandin E2 Protects Intestinal Tumors from Non-Steroidal Anti-inflammatory Drug-Induced Regression in ApcMin/+ Mice. Cancer Res. 62, 403-408, 2002

• Petrik, M.H., McEntee, M.F., Obukowicz, M.G., Masfarrer, J., Zwiefel, B., Chiu, C.-H. and Whelan, J. 2002. Selective Inhibition of ?-6 desaturase impedes Apc-Mediated Tumorigenesis. Cancer Lett. 175, 157-163.

• Whelan, J. and McEntee, M.F. 2001. Dietary Fats and APC-Driven Intestinal Tumorigenesis. In Nutrition and Gene Expression. (Eds. Berdanier, C.D. and Moustaid- Moussa, N.) CRC Press. Boca Raton, FL. pp. 231-260.

• Whelan, J., Petrik, M.H., McEntee, M.F.and Obuckowicz, M. 2001. Dietary EPA Reduces Tumor Load in ApcMin/+ Mice by Altering Arachidonic Acid Metabolism, but Conjugated Linoleic Acid, Gamma- and Alpha-Linolenic Acids Have No Effect. In Advances in Experimental Biology and Medicine, (Honn, K.V., Nigam, S., Marnett, L.J. and Dennis, E., Serhan, C. eds.) Plenum Publishing, NY.

Select Grants and Contracts (since 2001)
2006-08 The Consortium for Plant Biotechnology Research. Plant Biotechnology and Omega-3 Fats in Health and Disease. PI: Jay Whelan. Total Award: $674,699, (in review).

2003-08 National Institutes of Health. Transplacental Pancreatic Carcinogenesis by NNK.. PI: Hildegard Schuller, Co-PI: Jay Whelan and H.W.R.Wang. Total Award $1,450,000.

2002-04 American Institute for Cancer Research. Washington, D.C. "Prostaglandin E2 Receptors and intracellular calcium signaling in intestinal tumorigenesis”. Total Award: $159,692

2002-07 USDA Multistate Regional Project - NC1167. “Achieving Dietary Polyunsaturated Fatty Acid Recommendations for the Maintenance of Health and Prevention of Disease”. Jay Whelan and Kenneth Allen, Co-Authors and Co-Principal Investigators.

2000-03 United States Department of Defense (DOD), Washington, D.C. “Effect of N-3 and N-6 Polyunsaturated Fatty Acids on Growth and Progression of Prostatic Cancer in Vivo.” J. Whelan, Co-Principal Investigator, Michael McEntee, Principal Investigator. Total Award: $309,700.

2000-02 Research Grant from Pharmacia Company, St. Louis , MO. “Role of Cyclooxygenase-1 and/or -2 in the Mechanism of Intestinal Tumorigenesis". Total Award: $245,398.

2000-01 Research Grant from Pharmacia Company, St. Louis , MO. “Chemoprevention of Intestinal Tumorigenesis in the ApcMin\+ Mouse by Inhibition of avß3 Integrin". Total Award: $24,739.

1999-01 American Institute for Cancer Research. Washington, D.C. "Role of Arachidonic Acid and PGE2 as Key Mediators of Intestinal Tumorigenesis In Vivo”. Total Award: $158,484

1999-01 American Institute for Cancer Research. Washington, D.C. "In Vitro Effects of Resveratrol During Early Stages of Intestinal Tumorigenesis". J. Whelan, Co-Principal Investigator, Michael McEntee, Principal Investigator. Award: $75,952.

Select Presentation of Papers at Scientific Meetings (last 4 years)
2005 Annual meeting of the Society for Nutrition Education, “Dietary Omega-3 PUFAs: Does Form Matter?”, Orlando, FL, July 2005. (Invited Plenary Speaker).

2005 Lillian Fountain Smith Conference on Omega-3 Fatty Acids, “Dietary N-3 PUFAs: Form, Amount and Function”, Fort Collins, CO, June 2005, (Invited Plenary Speaker).

2005 Experimental Biology, Symposia on “N-3 Fatty Acids, Transitioning from Research to Education”, “Are all Dietary PUFAs the same?” April 2005. (Invited Plenary Speaker).

2005 Symposium on the "Calcium, Vitamin D, Dairy, and Prostate Cancer", National Dairy Council. Chicago, IL, January 1995. Invited Panel member.

2004 World Cancer Research Fund International/American Institute for Cancer Research International Research Conference on Food, Nutrition and Cancer, “How Dietary N-6 Polyunsaturated Fatty Acids Can Play a Role in Intestinal Tumorigenesis” , Washington, DC, July 2004, (Invited Plenary Speaker).

2004 6th Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL), “Dietary n-3 and n-6 PUFA: The Yin and Yang of Intestinal Tumorigenesis”, Brighton, UK, June 2004. (Invited Speaker).

2004 American Oil Chemists’ Society, Conference on Specialty Oils: Their Biochemistry and Physiology, “Omega-3 Fatty Acids and Intestinal Tumorigenesis”, Cincinnati, OH, May 2004. (Invited Plenary Speaker).

2003 FASEB Summer Conference on Inflammation and Chronic Diseases. “Fatty Acids and Intestinal Cancer”, Saxtons River, VT, July 2003. (Invited Plenary Speaker)

2003 Experimental Biology (FASEB), Symposium on "Improving Human Nutrition through Genomics, Proteomics and Biotechnology", San Diego, CA, April 2003 (Organized with Dr. Naima Moustaid-Moussa).

2002 Pharmacia Oncology and Pfizer, Inc., Oncology Consultants Meeting on COX-2 Specific Inhibition in Cancer Treatment and Prevention, Palm Beach, Florida, October, 2002. Invited Panel member

2001 NIH, USDA, ASNS and ODS (Office of Dietary Supplements) sponsored workshop on “Essential Fatty Acids in Health Maintenance and Disease Prevention”. Washington, D.C. March 20, 2001. (Invited Plenary Speaker)

2001 American Oil Chemists’ Society, Symposium on Physiological and Metabolic Aspects of CLA, “Dietary Conjugated Linoleic Acid on Intestinal Tumorigenesis in Min/+ Mice”, Minneapolis, MN, May 2001. (Invited Plenary Speaker).

2001 NIH, USDA, ASNS and ODS (Office of Dietary Supplements) sponsored workshop on Essential Fatty Acids in Health Maintenance and Disease Prevention, “Balancing Fatty Acids in the Body with Functional Foods” , Washington, D.C. March 2001. (Invited Plenary Speaker).

 

Contact the Department of Nutrition

1215 W. Cumberland Ave.
229 Jessie Harris Building
Knoxville, TN 37996-1920

Brenda Hart
bhart57@utk.edu

Phone: (865) 974-5445
Fax: (865) 974-3491